The SJLIFE cohort was established in 2007 to address knowledge deficits about the health of adults treated for cancer during childhood and adolescence.

Study Objectives/Aims

The objective of the St. Jude LIFE study is to establish a lifetime cohort of childhood cancer survivors to facilitate longitudinal clinical evaluation of health outcomes in aging adults surviving pediatric cancer.

Specific aims are to 1) determine prevalence and latency of late effects; 2) identify multifactorial predictors of adverse outcomes; 3) develop risk profiles for adverse health outcomes across the age spectrum; and 4) use data to guide health screening and risk-reducing interventions.